Like collagen, the body naturally produces glucosamine and is found in bones and articular cartilage. It is the combination of glucose and an amino acid called glutamine.

Several studies have demonstrated that glucosamine plays an essential role in maintaining joint health. In fact, it helps improve the quality of the synovial fluid (also called synovia). This liquid is secreted by the synovial membrane to lubricate and protect joints, among other things.

The body’s natural production of Glucosamine decreases with age.

Benefits of Glucosamine

When Glucosamine is combined with other joint beneficial ingredients, such as AminoLock® Collagen, we get very effective natural supplements for joint health.

For example, it has been clinically proven that AminoLock Collagen helps reduce joint discomfort. The collagen-glucosamine combination, as the one in Genacol Plus, for example, provides additional benefits by adding lubricating and protecting action to the joints.

Glucosamine is often combined with chondroitin and MSM for optimum results in promoting joint health. Genacol Optimum combines AminoLock Collagen with glucosamine, chondroitin and MSM, making it one of the most complete joint formula available.

Recommended dosage

The daily recommended glucosamine dosage is 1,500 mg.

Special attention

Glucosamine used to manufacture supplements is extracted from the shells of crustaceans such as crabs and shrimps. Seafood-allergic people should therefore pay particular attention before consumption, or even avoid it according to the intensity of their allergy. Recent clinical trials(1) also indicate that glucosamine, contrary to what was previously said, would not affect the sugar levels of people with diabetes. In conclusion, glucosamine may also interact with anticoagulant drugs.

In any case, when taking a new supplement, it is always important to consult with your pharmacist or health care provider whether taking glucosamine is right for you depending on your health and the current medications or supplements you are taking.


(1) A comprehensive review of oral glucosamine use and effects on glucose metabolism in normal and diabetic individuals. Simon RR, Marks V, et al. Diabetes Metab Res Rev. 2011 Jan;27(1):14-27.
(2) Potential glucosamine-warfarin interaction resulting in increased international normalized ratio: case report and review of the literature and MedWatch database. Knudsen JF, Sokol GH. Pharmacotherapy. 2008 Apr;28(4):540-8. Review.

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